
PE-22-28 (10mg)
* A novel peptide derived from spadin, researched for its neuroprotective, antidepressant, and cognitive-enhancing properties – showing promise in brain health and mental performance applications.
- Modulates TREK-1 channels to improve mood
- Studied for fast-acting antidepressant-like effects
- Supports neurogenesis & brain plasticity
- May enhance memory, focus & emotional resilience
- Non-sedative & well-tolerated in preclinical studies
- Ideal for nootropic, neuroregenerative, and mood research
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PE-22-28 is a synthetic peptide derived from the neuropeptide PACAP (pituitary adenylate cyclase-activating polypeptide). It is composed of a 7-amino-acid sequence with a specific focus on promoting neurorestorative and neuroprotective effects. This peptide has gained significant attention in the scientific community for its potential role in supporting brain health, repairing neural damage, and promoting cellular resilience.
PE-22-28 interacts with receptors in the nervous system to support various processes related to neurogenesis and cell protection. Its unique properties make it a versatile peptide for research focusing on neurological health, cognitive function, and the study of degenerative neural conditions.
Issued under Alpha Bio Med Labs, the authorized testing and distribution partner.

The amino acid sequence of PE-22-28 is as follows:
His-Ser-Asp-Gly-Phe-Leu-Arg
This short peptide is designed to mimic certain aspects of the parent PACAP molecule, delivering targeted effects while maintaining a simplified structure for ease of synthesis and research applications.
Neuroprotection
PE-22-28 has demonstrated promising neuroprotective effects, helping shield neurons from oxidative stress and damage caused by toxins or trauma. This peptide may support research into therapies for neurological conditions and brain injuries.
Promotes Brain Plasticity
Studies suggest that PE-22-28 fosters neurogenesis and synaptic plasticity, critical for learning, memory, and overall cognitive function. This property has positioned it as a candidate for research into cognitive enhancement and brain recovery.
Anti-Anxiety and Mood Support
PE-22-28 has shown potential in modulating mood and reducing anxiety-like behaviors in preclinical studies. Its impact on neurotransmitter systems makes it a compelling subject for research into mood regulation.
Cellular Resilience
By interacting with cellular pathways, PE-22-28 may enhance the resilience of neural and other tissue cells against stressors, contributing to overall cellular health and recovery.
Direct & scientific
- Backed by 60+ scientific studies
- BPC‑157 has demonstrated consistent healing results across muscle, nerve, and gut models — with early human data showing 92% of patients reporting pain relief.
“Accelerated Healing of Muscles, Ligaments, and Tendons”
Multiple animal and human case studies show BPC-157 significantly speeds up recovery of torn muscles, damaged ligaments, and tendon-to-bone healing — especially relevant for athletes and injury rehabilitation.
PUBMED — article link
BPC comparison to others
- Muscle & joint healing
- Repairs gut lining (IBS, IBD)
- Heals gut tissue
- Boosts blood flow
- Reduces Inflammation
- Activates stem cell repair
- Long-term gut support
- Clinically backed
Product quality guarantee
We are continuously conducting HPLC test on all of our raw powders as well as finished products to ensure the quality of our products. You can have the product you bought from us tested at any HPLC licensed testing facility and if the results are negative, we will refund the following:
- $100 HPLC test fee
- Total order amount
- Shipping costs
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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
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